Correction Pharmaceuticals has created a classic legend of the pharmaceutical industry in ten years. Many people will be curious-what is the force that promotes its rapid development and composes the "revision myth" that surprised the industry? What spirit made it win the trust of the people and extend the legendary story? With this curiosity, the author takes you into the correction pharmaceutical industry to find the answer.
Scientific and technological innovation——
Entering the Changchun Amendment Building, several eye-catching characters on the wall-"Management, Innovation, Reform, Coordination and Development" greeted guests from all directions. In fact, no matter if you modify the Tonghua Industrial Base, the Beijing Pharmaceutical Base, or the Sichuan Pharmaceutical Base, you will be surrounded by a strong innovation atmosphere of "everyone wants to innovate and everyone strives to be an innovation model." The spirit of innovation has been incorporated into the blood of corrections, becoming the coordinates of their actions.
As a large-scale modern pharmaceutical enterprise group integrating research, production and sales, Ambulatory Pharmaceuticals always adheres to technological innovation as a guide, strengthens research and development capabilities, and masters professional core technologies through independent development or cooperation with other scientific research institutions. Strengthen the construction of the scientific and technological innovation system, and form an innovation system that takes new product development and new technology as the leader, and supplements new industrial products, new technology assimilation, and new technology and equipment. This guarantees higher quality, better service, higher efficiency, greater differentiation, and more scientifically managed pharmaceutical products.
In this technological innovation system, its driving mechanism is consumer-led. That is to say, each innovation activity of the correction pharmaceutical industry is guided by the needs of "you", find out the technical functions and technical keys required by "you", combine the two, and continue to use market demand to Inspect, adjust and promote innovative activities.
For example, in 2000, a large number of market surveys of consumers learned that as many as 31.16% of women suffer from cervical and vaginal diseases. There is an urgent need on the market for a gynecological external product that has a significant effect, is convenient and clean. To this end, the revised medical experts have invested fully in this technological innovation project and successfully developed the revised Xiaomi suppository in a short period of time. Compared with similar products on the market, the Xiaomi suppository has a more sophisticated process and a higher level of technology. And specially formulated cotton tampons imported from the United States, providing great convenience and comfort for the majority of women patients. Once the product was launched, it immediately won the favor of consumers, with annual sales of more than several hundred million yuan. Even so, the technological innovation of the correction pharmaceutical industry has not stopped. After the market test, according to the feedback from the sales system, the modified pharmaceutical industry innovated and developed the three new types of Chinese traditional medicines—xiaoli lotion on the basis of Xiaomi Suppository. This product has been successfully declared and will be put on the market soon, which will provide a wider choice for patients' medication.
Many years of research by revision medical experts have found that if gastric and duodenal ulcers are not treated in time, they can lead to bleeding, perforation, pyloric obstruction, and canceration, which seriously endanger health. According to statistics from authoritative agencies, the risk of gastric and duodenal ulcer cancers is increasing year by year, and on average more than 300,000 people die from cancer every year in China. For this reason, under the guidance of the new treatment theory of "ulcer healing quality", over 300 scientific researchers in the pharmaceutical industry have successfully developed a new high-tech drug, Xinluowei, after nine years of hard work, which has been brand-new in 2006. Go public. The successful development of Xinluowei has brought new hope for rehabilitation for the majority of patients with gastric disease, and has been reviewed and evaluated as a national first-class biological new drug by the authoritative department. According to reports, the "Administrative Measures for Drug Registration" since 2002 has tightened the standards for new drugs. So far, the country has approved a total of 236 first-class new drugs, of which 228 are western medicines, 5 Chinese medicines, and only 3 biological medicines. At present, Xinluowei is a natural biological drug approved as "a new class of drugs" among ulcer drugs. Amendment Pharmaceuticals has all independent intellectual property rights and is a manufacturer. This fully reflects the R & D strength of Amendment Pharmaceuticals and the consumer Centered research and development direction!
In order to better meet the needs of consumers, serve consumers, amend the pharmaceutical industry and strengthen the network information construction of the group. By establishing an information management system with ERP as the core, the internal information construction of the group has been in line with the world. Through the comprehensive use of modern management technology, manufacturing technology, information and network technology, the three elements of the entire production process of the group are integrated and optimized organically, and the information flow and logistics are integrated with the modern enterprise system being implemented by the company. The tight integration of reforms, the close integration of corporate technological transformation, and the strategic objectives of business operation and development, through the implementation of informatization projects, build computer networks and database platforms and software systems covering all subsidiaries and branches of the entire group to achieve a comprehensive Enterprise information integration and sharing; realize the integrated management of enterprise planning, purchasing, production, inventory, sales, etc., to achieve multi-flow integration of logistics, information flow, capital flow; establish quality management and control of the entire product process; realize The automated management and control of the workshop; the establishment of a nationwide marketing network communication system and an enterprise e-commerce platform, and the realization of online marketing management, etc., make the correction pharmaceutical industry into a highly integrated modern enterprise group.
Scientific and technological innovation——
Improve scientific research strength
As everyone knows, the research and development of a drug, especially a new product, is a time-consuming and labor-intensive system engineering. Amend the pharmaceutical industry to invest heavily in order to turn scientific and technological achievements into productivity.
Amend a famous quote from the Chairman of the Pharmaceutical Group Xiu Xiugui: All of them must be innovative!
As early as 1999, Amend Pharmaceutical established a technology center. In 2000, it passed the provincial technology center certification, and in 2003 it passed the technology center certification.
After the establishment of the Technology Center, a large number of achievements have been made in process technology development, new product development, automatic control, and information network. The laboratory of traditional Chinese medicine preparations has been accredited as a secondary laboratory of Chinese medicine research in 2005. This is the first unit of a domestic pharmaceutical enterprise research institution to obtain the accreditation of a traditional Chinese medicine laboratory. It also marks that the Group's technology center laboratory has been recognized in terms of scientific and standardized management. Technical cooperation and development play a positive role in promoting.
The correction technology center adheres to independent research and development as the main body, integrates the strengths of scientific research institutes and colleges and universities, gathers the strengths of all the families, and serves the correction pharmaceutical industry. It has established cooperative relations with Tianjin University, Tsinghua University, Beijing Institute of Technology, Shenyang Pharmaceutical University, Jilin University, Changchun College of Traditional Chinese Medicine, Zhuhai Mintong Medical Research Institute, Changsha Weishen Pharmaceutical Development Co., Ltd. and other units. Cooperate with Tianjin University to develop key technologies for the modern production of Chinese medicine; Cooperate with Shenyang Pharmaceutical University to develop and develop the new drug Hongsongguo Tablets; Cooperate with Jilin University to develop and develop the national first-class new medicine thrombolytic hormone; Cooperate with Changchun College of Traditional Chinese Medicine to develop and develop National Refined Chinese herbal medicine granules with resembling traditional Chinese medicine; cooperating with Zhuhai Mintong Medical Research Institute to develop and develop national second-class new drug Geping (irbesartan); cooperating with Changsha Weishen Pharmaceutical Development Co., Ltd. to develop and develop national first-class new drug Gatifloxacin , Obtain new drug certificate and production approval and large-scale production.
In the construction of the technological innovation system, the Technology Center has established a complete set of intellectual property protection and incentive mechanisms for the invention of new processes, technologies and products. It has laid a solid foundation for the future development of enterprises. At the same time, institutional innovation should be strengthened to ensure the effective development of technological innovation. The Amendment Group brings out nearly one million yuan in innovation award funds each year, giving heavy awards to the company's technological innovation achievements and scientific research personnel, forming a healthy and innovative environment and atmosphere within the company.
Scientific and technological innovation——
Ignite high-growth engines
At present, the Amendment Pharmaceutical Technology Center is committed to grasping the key national support to improve the enterprise technology center's independent innovation capability platform construction project and build it into an excellent domestic new technology research and development laboratory.
At the same time, Amendment Pharmaceuticals conscientiously established eight production bases for preparations. Achieve a rational industrial manufacturing system including new formulations such as drip pills, film preparations, and freeze-dried powder injections.
Establish three major raw material production bases: a national traditional Chinese medicine standardized extract production base with automated integrated manufacturing technology control, a modern chemical raw material medicine production base, and a biological fermentation production base. Establish three bases for planting and breeding Chinese medicinal herbs of North and South Korea. Establish a medium-sized cosmetics production base and a health food, medicinal and dietary product production base.
According to the requirements of the company's development of new dosage forms, it will focus on equipping new dosage form production lines such as drip pills, pellets, freeze-dried powder needles, dry granulation, plasters, film preparations, gels, etc. Equipped with domestic excellent automated integrated manufacturing technology control systems and new technology equipment for extraction and separation of traditional Chinese medicines in the production base of standardized raw materials for traditional Chinese medicine and biological fermentation bases.
In the past few years, based on market research, Amend Pharmaceutical Technology Center has increased the development of new products, developed more than a hundred new products, and successfully developed a new class of national chemical drugs Gatifloxacin, which has been used to treat high The new national drug of blood pressure, Geping (irbesartan) and etopril hydrochloride, the national first-class new drug "thrombolysin" with independent intellectual property rights, has entered the stage of pharmacodynamics and toxicology research. . More than 60 varieties of medicines, health foods, cosmetics and health supplies will be developed, which will become a new economic growth point for the future revision of the pharmaceutical industry.
Driven by the strong promotion of technological innovation, what is displayed in front of the correction pharmaceutical industry is a spacious road leading to the world's hundred compulsory pharmaceutical companies. High-tech pharmaceutical enterprises with high starting points, large scale, modern systems, scientific management, advanced technology, sophisticated equipment, and striving to be in line with international standards are being established.
At present, Amend Pharmaceutical has become a large-scale modern medical enterprise group that integrates scientific research, production, chain management, standardized cultivation of traditional Chinese medicine, sika deer breeding, and product deep processing. The economic benefits of enterprises have been rising year after year!
In the future, the correction pharmaceutical industry will maintain a strong momentum of development, relying on the advantages of technological innovation, to provide patients with more scientific, more effective, more affordable, and more conscience medicine, reassurance medicine, tube medicine more in line with the needs of the people!
Scientific and technological innovation——
Be the King of Chinese Medicine
In revising the overall plan of the pharmaceutical industry, the main directions and characteristics of the development of modern Chinese medicine were highlighted. Highlight the application of new Chinese medicine extraction and separation technology, bioengineering technology and modern preparation technology in the development of traditional Chinese medicine innovative drugs and secondary development of traditional Chinese medicine. The secondary development of traditional Chinese medicine varieties with accurate curative effect, high safety, good market foundation, or market competitiveness, and strive to achieve the strategic goal of becoming the leading modern Chinese medicine leader enterprise at the fastest speed.
For the existing varieties, the revised technology center conducts integrated screening to highlight the characteristics and development direction of modern Chinese medicine. Through the application of new technologies and processes, the efficacy of drugs is improved. For example, "Starch", one of the ingredients belladonna is traditional Chinese medicine for thousands of years. Compared with the "Belladonna Extract" used by general pharmaceutical companies, Starshu uses the "Belladonna Extract". Ultrasonic extraction method is used to extract the main active ingredient in belladonna—Phosphine, and then the membrane separation technology is used to remove the macromolecular impurities in the extract, so as to increase the content of the active ingredient in the extract and improve the efficacy. Advanced technologies such as thin-layer chromatography are also used to detect the "belladonna extract". At the same time, content determination items are added. Quantitative detection using high-performance liquid chromatography reduces human error and improves data accuracy. Starshu fully ingested the essence of Belladonna, removed impurities, dregs and harmful substances, and increased the active ingredients of the drug multiple times, making the patient's medication safer!
The application of new technology and new technology will also greatly improve the purity and effectiveness of the drug, making the effect of the drug more precise. For example, the traditional method of taking traditional Chinese medicine is to boil the whole herb in a pot. In addition to the active ingredients in this soup, there are also some harmful substances. The company's technical center of Amendment Pharmaceuticals, through technological innovation, uses low-temperature separation technology, carbon dioxide hyperlink extraction technology and other methods to retain the active ingredients of the drug and remove harmful substances. The produced medicine can be treated symptomatically and directly to the lesion, and the effect is of course more precise!
In the past 7 years, the technology center has focused on research and development and quality research of Chinese medicine extraction and separation technology, modern preparation technology. In professional fields such as biotechnology, pharmacology and toxicology, and in the introduction of new technologies and new special products, we have carried out close cooperation with scientific research institutes to achieve complementary advantages, improve overall innovation capabilities, and accelerate the development and industrialization of new products. The pace of marketization. More and better undertake key projects and topics on the industrialization of new technologies of Chinese medicine modernization and industrialization of biopharmaceutical technology, and make due contributions to the development of China's pharmaceutical science and technology.
Based on the modernization of traditional Chinese medicine, Amend Pharmacy strives to improve its competitiveness and participate in the competition with "foreign Chinese medicine". After 10 years of efforts, the product structure of the revised pharmaceutical industry will be more reasonable, the market structure will be clearer, and new and special products with high-tech content and clear intellectual property rights will gradually enter the market.